N,N-Dimethylformamide

Code: S227056-1L

N,N-Dimethylformamide (DMF) is a popular solvent used in chemical processes. DMF is an effective solvent for isolating chlorophyll from plant tissues. It is a common reagent in organic synthesis. It serves as a solvent, dehydrating agent, reducing agent, and catalyst in a variety of processes. It is a versatile building block used in the synthesis of compounds with functional groups such as O, -CO, -NMe2, -CONMe2, -Me, and -CHO.

per 1L
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N,N-Dimethylformamide

The solvent N,N-dimethylformamide (anhydrous) was utilized in the production of the cytotoxic luteinizing hormone-releasing hormone (LH-RH) combination AN-152 (a chemotherapeutic medication) and the fluorophore C625 [4-(N,N-diphenylamino)-4′-(6-O-hemiglutarate)hexylsulfinyl stilbene].It can be used as a solvent medium in different organic reduction processes.

The following processes have employed DMF as a solvent:

L-azidohomoalanine (L-Aha) synthesis in multiple steps during mesylate replacement with sodium azide.

The synthesis of phosphine-FLAG, a detection reagent for metabolic glycan tagging.

Per-O-acetylated 6-azidofucose, a per-O-acetylated azido sugar, is synthesized.

Many hydrophobic organic molecules can be dissolved in it.