1-Hydroxybenzotriazole hydrate

Code: S54802-250G-F

A coupling agent called 1-hydroxybenzotriazole is utilized to create amides by a condensation reaction between activated ester/acids and the protected amino acids' amino groups. During the synthesis of peptides, it also functions as a racemization suppressor.

per 250G
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 1-Hydroxybenzotriazole hydrate

1-Hydroxybenzotriazole hydrate can be used as a condensation reagent to prepare:

  • Poly-γ-glutamic acid methyl ester from a dimer of γ-glutamic acid.
  • Oxadiazoles via cyclo condensation of amidoximes with trifluoroacetic anhydride or benzoic acid derivatives.